- Daggett Museum
The Daggett Museum consists of more than 40 cases displaying Early American collectibles, Railroad China, Navajo Indian Code-talkers from WWII, Barbed wire, Lapidary work and much more, including a unique model of the nearby Solar I Generating Plan.
- Desert Discovery Center
The Desert Discovery Center at 831 Barstow Rd. has exhibits, a desert trail to explore, and is home to the Old Woman Springs Meteorite, the second largest space rock ever found in the United States. The center is a partnership between Barstow Community College, Barstow Unified School District, Bureau of Land Management, City of Barstow and the Mojave Valley River Museum.
- Mojave River Valley Museum
The museum houses a series of displays and exhibits that portray the history of the Mojave River Valley from the arrival of Father Garces in 1776 on through pathfinders, pioneers, miners, railroads and the present space program. Their archive of local-area newspapers dates back to 1911 and their photo collection contains more than 20,000 photos.
- Route 66 Museum
The Route 66 "Mother Road" Museum was dedicated on July 4, 2000, in the historic Casa del Desierto, Harvey House, in Barstow, California. The Museum displays a collection of historic photographs and artifacts related to Route 66 and the Mojave Desert Communities. Displays include development of the United States Route 66 from early pioneer trails, railroads, automotive history, businesses and sites.
- Western America Railroad Museum
Located within historic Harvey House, the Western America Railroad Museum houses railroad memorabilia from not only the Barstow area, but from the entire West as well. Old locomotives, photos and archives are available for public viewing. There are also two cabooses open for tours.